Antibody-Drug Conjugates

Antibody-drug conjugates or ADCs are an important class of highly potent biopharmaceutical drugs designed as a targeted therapy for the treatment of cancer. The antibody-drug conjugate or ADC is a three-component system including a potent cytotoxic anticancer agent linked via a biodegradable linker to an antibody. The antibody binds to specific markers (antigens or receptors) at the surface of the cancer cell. The whole antibody-drug conjugate is then internalised within the cancer cell, where the linker is degraded, and the active drug released.

Due to the complexity of these molecules it is important that you pick an analytical partner that understands the specialised and technically challenging nature of ADCs and marry that with the talent and experience to running a huge variety of different assay formats.

Our services include a diverse range of assay formats

Cell-based Binding Assays (Flow Cytometry & ELISA)
Cell Death & Apoptosis
Cell Proliferation & Viability
Cell Signalling
Cytokine Secretion/Inhibition
Trogocytosis
Ligand Binding assays
Reporter Gene Assays
Custom Assay Development

Contact us to discuss our ADC services