Complex Analysis

Investigatory bioassays provide solutions to sound hypotheses associated with a monoclonal antibody-based drug molecule. These exploratory assays aim to provide a deeper understanding of potential in vivo activities.

With a comprehensive understanding of the MOAs of both biosimilars and NBE antibodies coupled with world class approaches for in vitro characterisation, Antibody Analytics is well placed to both assist you in defining appropriate approaches and performing complex testing.

Examples of such assays include:

Mixed Lymphocyte Reaction (MLR)
Characterise the ability of the drug to recruit the immune response, through T-cell activation, to target the tumour microenvironment
Functional T-cell Suppression/Killing
Evaluate the ability of an anti-inflammatory drug candidate to suppress the T-cell mediated immune response.

PBMC and T-cell Stimulation
Understand how cells of the immune system are activated and recruited by the drug molecule.
Cytotoxic T Cell Assays
Measure the potency of T-cell engaging bispecific antibodies

Antibody Analytics can support your molecule development through well designed and comprehensive approaches to mAb characterisation

Antibody Analytics can support your molecule development through well designed and comprehensive approaches to mAb characterisation

Contact us to find out more...