Our team has experience in generating genetically engineered cell lines for a variety of purposes. In addition to standard cell line production where a gene of interest is constitutively expressed in an immortalised cell line background, we have created bespoke engineered cell lines for a variety of downstream purposes. These include over-expression of proteins for protein purification (e.g. purified receptor generation), creation of inducible promoter cell lines, reporter gene expression and even difficult to engineer primary cells such as T cells with chimeric antigen receptors.

Our team will advise on the selection of cellular background and appropriate promoter combination to meet your needs, coupling this with our crafted strategies to ensure rapid stable cell line production while maximising gene expression. 

Need to test your newly-created cell line in a functional or cell-based assay? We can support that too. We can meet both your target and effector cell needs, with our range of immortalised cell lines, custom engineering services and large stocks of primary human immune cells at our disposal.